DNA Damage Atlas



Basic Information

Dataset ID:

  GSE153734


PMID:

  34389725


Technique Type:

  EdU-seq


Publication:

  A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells


First Author:

  Rebecca A. Dagg


Last Author:

  Madalena Tarsounas


Year:

  2021


Journal:

  Nature Communications


Access Link:   

Samples ( 20 )

  Sample Name    Cell Line/Tissue    Organism    Treatment    Genotype    In-situ Treatment    Cell Phase    Bait/Targeted Break    Technique    fastqc  
GSM4650333-EdUseq-HU_of_DMSO-treated_BRCA2-proficient_H1299_cells_10_h_after_mitotic_shake-offH1299Homo sapiensDMSOBRCA2-proficient///EdU-seq
GSM4650334-EdUseq-HU_of_LY2090314-treated_BRCA2-proficient_H1299_cells_10_h_after_mitotic_shake-offH1299Homo sapiensGSK3 inhibitorBRCA2-proficient///EdU-seq
GSM4650335-EdUseq-HU-release_of_DMSO-treated_H1299_BRCA2-proficient_cells_10_h_HU_arrest_and_release_for_3_hH1299Homo sapiensDMSOBRCA2-proficient///EdU-seq
GSM4650336-EdUseq-HU-release_of_LY2090314-treated_H1299_BRCA2-proficient_cells_10_h_HU_arrest_and_release_for_3_hH1299Homo sapiensGSK3 inhibitorBRCA2-proficient///EdU-seq
GSM4650337-EdUseq-HU_of_DMSO-treated_BRCA2-deficient_H1299_cells_20_h_after_mitotic_shake-offH1299Homo sapiensDMSOBRCA2-deficient///EdU-seq
GSM4650338-EdUseq-HU_of_LY2090314-treated_BRCA2-deficient_H1299_cells_20_h_after_mitotic_shake-offH1299Homo sapiensGSK3 inhibitorBRCA2-deficient///EdU-seq
GSM4650339-EdUseq-HU-release_of_DMSO-treated_H1299_BRCA2-deficient_cells_20_h_HU_arrest_and_release_for_3_hH1299Homo sapiensDMSOBRCA2-deficient///EdU-seq
GSM4650340-EdUseq-HU-release_of_LY2090314-treated_H1299_BRCA2-deficient_cells_20_h_HU_arrest_and_release_for_3_hH1299Homo sapiensGSK3 inhibitorBRCA2-deficient///EdU-seq
GSM4650341-EdUseq-HU_of_DMSO-treated_BRCA2-proficient_H1299_cells_12_h_after_mitotic_shake-offH1299Homo sapiensDMSOBRCA2-proficient///EdU-seq
GSM4650342-EdUseq-HU_of_LY2090314-treated_BRCA2-proficient_H1299_cells_12_h_after_mitotic_shake-offH1299Homo sapiensGSK3 inhibitorBRCA2-proficient///EdU-seq
GSM4650343-EdUseq-HU-release_of_DMSO-treated_H1299_BRCA2-proficient_cells_12_h_HU_arrest_and_release_for_2_hH1299Homo sapiensDMSOBRCA2-proficient///EdU-seq
GSM4650344-EdUseq-HU-release_of_LY2090314-treated_H1299_BRCA2-proficient_cells_12_h_HU_arrest_and_release_for_2_hH1299Homo sapiensGSK3 inhibitorBRCA2-proficient///EdU-seq
GSM4650345-EdUseq-HU_of_DMSO-treated_BRCA2-deficient_H1299_cells_16_h_after_mitotic_shake-offH1299Homo sapiensDMSOBRCA2-deficient///EdU-seq
GSM4650346-EdUseq-HU_of_LY2090314-treated_BRCA2-deficient_H1299_cells_16_h_after_mitotic_shake-offH1299Homo sapiensGSK3 inhibitorBRCA2-deficient///EdU-seq
GSM4650347-EdUseq-HU-release_of_DMSO-treated_H1299_BRCA2-deficient_cells_16_h_HU_arrest_and_release_for_2_hH1299Homo sapiensDMSOBRCA2-deficient///EdU-seq
GSM4650348-EdUseq-HU-release_of_LY2090314-treated_H1299_BRCA2-deficient_cells_16_h_HU_arrest_and_release_for_2_hH1299Homo sapiensGSK3 inhibitorBRCA2-deficient///EdU-seq
GSM4650349-EdUseq-HU_of_DMSO-treated_BRCA1-WT_RPE1_cells_10_h_after_mitotic_shake-offRPE1Homo sapiensDMSOBRCA1+/+///EdU-seq
GSM4650350-EdUseq-HU_of_LY2090314-treated_BRCA1-WT_RPE1_cells_10_h_after_mitotic_shake-offRPE1Homo sapiensGSK3 inhibitorBRCA1+/+///EdU-seq
GSM4650351-EdUseq-HU_of_DMSO-treated_BRCA1-KO_RPE1_cells_20_h_after_mitotic_shake-offRPE1Homo sapiensDMSOBRCA1-/-///EdU-seq
GSM4650352-EdUseq-HU_of_LY2090314-treated_BRCA1-KO_RPE1_cells_20_h_after_mitotic_shake-offRPE1Homo sapiensGSK3 inhibitorBRCA1-/-///EdU-seq


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