DNA Damage Atlas


GSM3714906-END_seq_aB_TOP2Bko_0_5h_rep1




Basic Information

Manual

Sample ID:   

SRR8870124


Source Project ID:   

GSE129524

Cell Type:   

Reconsituted B cell


Organism:   

Mus musculus


Strain:   

C57BL/6


Treatment:   

Etoposide


Treatment Time:   

0.5hr


Treatment Dose:   

50uM


Genotype:   

TOP2B-/-


In-situ Treatment:   

Exo VII + Exo T


Spike-in Intensity:   

no spike in


Layout:   

SINGLE


Instrument model:   

Illumina NextSeq 550


Technique:   

END-seq


Others:   

control: GSM3714911-END_seq_aB12h_NT_re-used


Fastqc:  




Genome Browser

Manual

  link to genome browser visualization (rDNA locus is firstly shown for human and mouse samples)




Telomere Analysis

Manual

Ratio of (G-rich strand/C-rich strand): 0.723604



Quantification

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Peak Intensity Top 10 Peaks
Chromosome Start End Summit Intensity Strand
chr698895639890280988996727.5507+
chr1010600470910600500410600470913.8926+
chr710442762210442854410442806310.2236-
chr93595238235952600359524005.63988+
chr91239278631239301901239291054.64957-
chr82036898020377163203700054.55758+
chrX1267673611267741961267707874.52104-
chr82035696920362724203585094.32976+
chr131112219201112225081112223084.32135+
chr82036273520365209203646234.30704+
Download the Full Peak List



Overlapped Peaks from Replicates




Average Peak Intensity Top 10 Merged Peaks
Chromosome Start End Summit Intensity Strand
chr698895639890280988996729.386+
chr1010600470910600500410600470913.3911+
chr710442762210442854410442806310.5693-
chr91239278631239301901239291054.3397-
chrX1532196221532200581532198223.91271-
chr97195122071951715719514343.86801-
chr41460545141460577881460557543.75542+
chr113468165034682090346818503.5393-
chr41454477621454489921454480723.47978-
chr172450225424502527245024723.45615-
Download the Full Merged Peak List



Motif Analysis

Manual





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