DNA Damage Atlas


GSM5509035-PreB-Lig4-12hrs-AsisI-ENDseq-DNA2i-EXO1i-rep2




Basic Information

Manual

Sample ID:   

SRR15370044


Source Project ID:   

GSE181669

Cell Type:   

Abel pre-B cell


Organism:   

Mus musculus


Treatment:   

DNA2 inhibitor + EXO1 inhibitor


Treatment Time:   

12hrs


Treatment Dose:   

2uM DNA2i + 20uM EXO1i


Genotype:   

Lig4-/-


In-situ Treatment:   

Exo VII + Exo T


Harvested Time:   

12hrs


Cell Phase:   

G1


Targeted break:   

AsisI (12hrs)


Spike-in Intensity:   

no spike in


Layout:   

SINGLE


Instrument model:   

Illumina NexSeq550


Technique:   

END-seq


Fastqc:  




Genome Browser

Manual

  link to genome browser visualization (rDNA locus is firstly shown for human and mouse samples)




Telomere Analysis

Manual

Ratio of (G-rich strand/C-rich strand): 0.003727



Quantification

Manual

Peak Intensity Top 10 Peaks
Chromosome Start End Summit Intensity Strand
chr3115888066115888069/2103400/
chr3146812666146812669/1751770/
chr3116808386116808389/1599370/
chr137570811275708115/1502960/
chr159939343499393437/1293790/
chr57329285273292855/1190190/
chr119820368398203686/1121200/
chr23223600532236008/1104740/
chr4139192791139192794/1066470/
chr1130716976130716979/1066230/
Download the Full Peak List



Overlapped Peaks from Replicates




Average Peak Intensity Top 10 Merged Peaks
Chromosome Start End Summit Intensity Strand
chr3115888066115888069/2826215/
chr3146812666146812669/2393620/
chr3116808386116808389/2110900/
chr137570811275708115/1986455/
chr159939343499393437/1670490/
chr57329285273292855/1526745/
chr23223600532236008/1431130/
chr119820368398203686/1413685/
chr4139192791139192794/1381860/
chr21899744618997449/1360720/
Download the Full Merged Peak List




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