DNA Damage Atlas


GSM5509039-PreB-Lig4-53BP1-12hrs-AsisI-ENDseq-DNA2i-EXO1i-rep2




Basic Information

Manual

Sample ID:   

SRR15370049


Source Project ID:   

GSE181669

Cell Type:   

Abel pre-B cell


Organism:   

Mus musculus


Treatment:   

DNA2 inhibitor + EXO1 inhibitor


Treatment Time:   

12hrs


Treatment Dose:   

2uM DNA2i + 20uM EXO1i


Genotype:   

Lig4-/-53BP1-/-


In-situ Treatment:   

Exo VII + Exo T


Harvested Time:   

12hrs


Cell Phase:   

G1


Targeted break:   

AsisI (12hrs)


Spike-in Intensity:   

no spike in


Layout:   

SINGLE


Instrument model:   

Illumina NexSeq550


Technique:   

END-seq


Fastqc:  




Genome Browser

Manual

  link to genome browser visualization (rDNA locus is firstly shown for human and mouse samples)




Telomere Analysis

Manual

Ratio of (G-rich strand/C-rich strand): 0.003371



Quantification

Manual

Peak Intensity Top 10 Peaks
Chromosome Start End Summit Intensity Strand
chr3115888066115888069/1962540/
chr3146812666146812669/1896240/
chr3116808386116808389/1752390/
chr137570811275708115/1444510/
chr159939343499393437/1290460/
chr9121477512121477515/1147410/
chr38918799989188002/1140710/
chr57329285273292855/1134780/
chr137327200373272006/1124370/
chr4139192791139192794/1085710/
Download the Full Peak List



Overlapped Peaks from Replicates




Average Peak Intensity Top 10 Merged Peaks
Chromosome Start End Summit Intensity Strand
chr3115888066115888069/2263185/
chr3146812666146812669/2102005/
chr3116808386116808389/1987110/
chr137570811275708115/1670320/
chr159939343499393437/1454355/
chr9121477512121477515/1373475/
chr57329285273292855/1285640/
chr137327200373272006/1270515/
chr4139192791139192794/1237135/
chr23223600532236008/1200310/
Download the Full Merged Peak List




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