DNA Damage Atlas


GSM6428059-iNeuron_sgTDG_ddC_S1ENDseq




Basic Information

Manual

Sample ID:   

SRR20749648


Source Project ID:   

GSE210314

Cell Type:   

iNeuron


Organism:   

Homo sapiens


Treatment:   

ddC


Treatment Time:   

18 hrs prior to cell harvesting


Treatment Dose:   

40μM


Genotype:   

TDG CRISPRi


In-situ Treatment:   

Exo VII + Exo T + S1


Harvested Time:   

day7


Spike-in Intensity:   

no spike in


Layout:   

SINGLE


Instrument model:   

NextSeq 550


Technique:   

END-seq


Others:   

control: GSM6428058-iNeuron_WT_controlfor_sgTDG_ddC_S1ENDseq


Fastqc:  




Genome Browser

Manual

  link to genome browser visualization (rDNA locus is firstly shown for human and mouse samples)




Telomere Analysis

Manual

Ratio of (G-rich strand/C-rich strand): 0.012358



Quantification

Manual

Peak Intensity Top 10 Peaks
Chromosome Start End Summit Intensity Strand
chr9_gl000199_random33843350853442730.0769+
chr9_gl000199_random43764470744424811.6462+
chr9_gl000199_random1667691693561680608.84604+
chrUn_gl0002141163241192491181657.68103-
chrUn_gl0002281179251197051185747.55974-
chr9_gl000199_random1290661316681313347.47636-
chr19_gl000208_random1313382225.08912-
chr127703575770410077037764.14872-
chrUn_gl0002251109761118251112413.76033-
chr71476525331476527431476527433.69406-
Download the Full Peak List



Overlapped Peaks from Replicates




Average Peak Intensity Top 10 Merged Peaks
Chromosome Start End Summit Intensity Strand
chr13212172692121727021217270268.051-
chr616875996116875996516875996155.8838+
chr610266382810266383110266383149.6799-
chr9_gl000199_random34190350853442738.3473+
chr753627425536274395362743918.1083-
chrUn_gl00021240464414734096315.8037+
chr115449076015449078015449078015.6475-
chr468026542680265566802654214.9081+
chr19_gl000208_random1347022213.8485-
chr1199680871996808849968087112.6048+
Download the Full Merged Peak List



Motif Analysis

Manual





Copyright © 2023 All Rights Reserved by Wu lab