DNA Damage Atlas


GSM6428063-iNeuron_sgTDG_ddC_S1ENDseq_rep2




Basic Information

Manual

Sample ID:   

SRR20749646


Source Project ID:   

GSE210314

Cell Type:   

iNeuron


Organism:   

Homo sapiens


Treatment:   

ddC


Treatment Time:   

18 hrs prior to cell harvesting


Treatment Dose:   

40μM


Genotype:   

TDG CRISPRi


In-situ Treatment:   

Exo VII + Exo T + S1


Harvested Time:   

day7


Spike-in Intensity:   

no spike in


Layout:   

SINGLE


Instrument model:   

NextSeq 550


Technique:   

END-seq


Others:   

control: GSM6428062-iNeuron_WT_controlfor_sgTDG_ddC_S1ENDseq_rep2


Fastqc:  




Genome Browser

Manual

  link to genome browser visualization (rDNA locus is firstly shown for human and mouse samples)




Telomere Analysis

Manual

Ratio of (G-rich strand/C-rich strand): 0.020665



Quantification

Manual

Peak Intensity Top 10 Peaks
Chromosome Start End Summit Intensity Strand
chrUn_gl00021240464414734090928.6208-
chr9_gl000199_random34190353753449826.7543-
chr1111291724611291788011291763022.5637+
chr19_gl000208_random447015715.4448+
chr2233658517336594603365872313.4039-
chr418665306218665328218665306512.8427+
chrUn_gl00021680141811448070612.1573-
chr1917790041779913177945710.7643+
chr9_gl000199_random13021213167813133410.671-
chr74187472418835841881959.56676-
Download the Full Peak List



Overlapped Peaks from Replicates




Average Peak Intensity Top 10 Merged Peaks
Chromosome Start End Summit Intensity Strand
chr13212172692121727021217269268.051+
chr598452102984521049845210496.7058-
chr1442032653420326554203265389.2704+
chr417969285917969286217969286254.5729-
chr9_gl000199_random34190350853449838.3473-
chr217391843217391843617391843237.1881+
chr1828516076285160832851607631.8995+
chr1210153060910153061610153060923.4021+
chr323417189234171972341718920.4648+
chr195029199502930950293017.5916-
Download the Full Merged Peak List



Motif Analysis

Manual





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