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DNA Damage Atlas |
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DNA Damage Atlas |
Basic Information
Dataset ID:
GSE166119
PMID:
34852229
Technique Type:
LAM-HTGTS
Publication:
Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7
First Author:
Pawel M Switonski
Last Author:
Albert R La Spada
Year:
2021
Journal:
Cell Reports
Access Link:
Samples ( 8 )
| Sample Name | Cell Line/Tissue | Organism | Treatment | Genotype | In-situ Treatment | Cell Phase | Bait/Targeted Break | Technique | fastqc |
| GSM5061961-Neuro-2A_DACH1_10Q | Neuro-2a cell | Mus musculus | Transfected with plasmids encoding ataxin-7 10Q, spCas9 and sgRNA for site 1 from PX458 | / | / | / | / | LAM-HTGTS | |
| GSM5061962-Neuro-2A_DACH1_92Q | Neuro-2a cell | Mus musculus | Transfected with plasmids encoding ataxin-7 92Q, spCas9 and sgRNA for site 1 from PX458 | / | / | / | / | LAM-HTGTS | |
| GSM5061963-Neuro-2A_DACH1_non_targeting | Neuro-2a cell | Mus musculus | Transfected with plasmids encoding spCas9 and non-targeting sgRNA from PX458 | / | / | / | / | LAM-HTGTS | |
| GSM5061964-Neuro-2A_DACH1_posCtrl | Neuro-2a cell | Mus musculus | Transfected with plasmids encoding spCas9 and sgRNA for site 1 from PX458 | / | / | / | / | LAM-HTGTS | |
| GSM5061965-Neuro-2A_SUPT16_10Q | Neuro-2a cell | Mus musculus | Transfected with plasmids encoding ataxin-7 10Q, spCas9 and sgRNA for site 2 from PX458 | / | / | / | / | LAM-HTGTS | |
| GSM5061966-Neuro-2A_SUPT16_92Q | Neuro-2a cell | Mus musculus | Transfected with plasmids encoding ataxin-7 92Q, spCas9 and sgRNA for site 2 from PX458 | / | / | / | / | LAM-HTGTS | |
| GSM5061967-Neuro-2A_SUPT16_non_targeting | Neuro-2a cell | Mus musculus | Transfected with plasmids encoding spCas9 and non-targeting sgRNA from PX458 | / | / | / | / | LAM-HTGTS | |
| GSM5061968-Neuro-2A_SUPT16_posCtrl | Neuro-2a cell | Mus musculus | Transfected with plasmids encoding spCas9 and sgRNA for site 2 from PX458 | / | / | / | / | LAM-HTGTS |
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