DNA Damage Atlas





Basic Information

Dataset ID:

  GSE163912


PMID:

  34135108


Technique Type:

  LAM-HTGTS


Publication:

  Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease.


First Author:

  Annalisa Lattanzi


Last Author:

  Matthew H Porteus


Year:

  2021


Journal:

  Sciene Translational Medicine


Access Link:   


Samples ( 6 )

  Sample Name    Cell Line/Tissue    Organism    Treatment    Genotype    In-situ Treatment    Cell Phase    Bait/Targeted Break    Technique    fastqc  
GSM4990616-RFe003_DPD190_WT_1CD34+ HSPCsHomo sapiensResuspended in P3 buffer with complexed Cas9:HBB RNPs + electroporated using the Lonza 4D Nucleofector////LAM-HTGTS
GSM4990617-RFe003_DPD190_HiFi_1CD34+ HSPCsHomo sapiensResuspended in P3 buffer with complexed Cas9:HBB RNPs + electroporated using the Lonza 4D Nucleofector///HBBLAM-HTGTS
GSM4990618-RFe003_DPD190_WT_2CD34+ HSPCsHomo sapiensResuspended in P3 buffer with complexed Cas9:HBB RNPs + electroporated using the Lonza 4D Nucleofector////LAM-HTGTS
GSM4990619-RFe003_DPD190_HiFi_2CD34+ HSPCsHomo sapiensResuspended in P3 buffer with complexed Cas9:HBB RNPs + electroporated using the Lonza 4D Nucleofector///HBBLAM-HTGTS
GSM4990620-RFe003_DPD190_WT_3CD34+ HSPCsHomo sapiensResuspended in P3 buffer with complexed Cas9:HBB RNPs + electroporated using the Lonza 4D Nucleofector////LAM-HTGTS
GSM4990621-RFe003_DPD190_HiFi_3CD34+ HSPCsHomo sapiensResuspended in P3 buffer with complexed Cas9:HBB RNPs + electroporated using the Lonza 4D Nucleofector///HBBLAM-HTGTS


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