DNA Damage Atlas



Basic Information

Dataset ID:

  GSE129528


PMID:

  31202577


Technique Type:

  HTGTS


Publication:

  Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity


First Author:

  Andres Canela


Last Author:

  André Nussenzweig


Year:

  2019


Journal:

  Molecular Cell


Access Link:   

Samples ( 10 )

  Sample Name    Cell Line/Tissue    Organism    Treatment    Genotype    In-situ Treatment    Cell Phase    Bait/Targeted Break    Technique    fastqc  
GSM3714945-HTGTS_PB_ZFN_NT_NT_1_TOPOAbel pre-B cellMus musculusNTLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714946-HTGTS_PB_ZFN_NT_NT_2_TOPOAbel pre-B cellMus musculusNTLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714947-HTGTS_PB_ZFN_ETO_NT_1_TOPOAbel pre-B cellMus musculusEtoposideLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714948-HTGTS_PB_ZFN_ETO_NT_2_TOPOAbel pre-B cellMus musculusEtoposideLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714949-HTGTS_PB_ZFN_IFN_NT_TOPOAbel pre-B cellMus musculusmouse interferon betaLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714950-HTGTS_PB_ZFN_IFN_ETO_TOPOAbel pre-B cellMus musculusEtoposide + mouse interferon betaLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714951-HTGTS_PB_ZFN_DRB_NT_TOPOAbel pre-B cellMus musculusDRBLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714952-HTGTS_PB_ZFN_DRB_ETO_TOPOAbel pre-B cellMus musculusDRB + EtoposideLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714953-HTGTS_PB_ZFN_NT_ASISIAbel pre-B cellMus musculusNTLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS
GSM3714954-HTGTS_PB_ZFN_DRB_ASISIAbel pre-B cellMus musculusDRBLIG4-/-G1/Tcrβ enhancer on chromosome 6HTGTS


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