DNA Damage Atlas |
Basic Information
Dataset ID:
 GSE108172
PMID:
 32769985
Technique Type:
 i-BLESS + ChIP-seq
Publication:
 Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites
First Author:
 Alexy Promonet
Last Author:
 Philippe Pasero
Year:
 2020
Journal:
 Nature Communications
Access Link:  
Samples ( 16 )
Sample Name | Cell Line/Tissue | Organism | Treatment | Genotype | In-situ Treatment | Cell Phase | Bait/Targeted Break | Technique | fastqc |
GSM2891678-prpa_TOP1_IP_2_1 | HeLa | Homo sapiens | NT | shTOP1 | / | / | / | ChIP-seq (anti-RPA) | |
GSM2891677-prpa_TOP1_INP_2_1 | HeLa | Homo sapiens | NT | shTOP1 | / | / | / | ChIP-seq (Input) | |
GSM2891676-prpa_HeLa_IP_2_1 | HeLa | Homo sapiens | NT | WT | / | / | / | ChIP-seq (anti-RPA) | |
GSM2891675-prpa_HeLa_INP_2_1 | HeLa | Homo sapiens | NT | WT | / | / | / | ChIP-seq (Input) | |
GSM2891674-prpa_ASF_IP_2_1 | HeLa | Homo sapiens | NT | shASF | / | / | / | ChIP-seq (anti-RPA) | |
GSM2891673-prpa_ASF_INP_2_1 | HeLa | Homo sapiens | NT | shASF | / | / | / | ChIP-seq (Input) | |
GSM2891669-gh2ax_ASF_IP_2_1 | HeLa | Homo sapiens | Doxycycline | shASF | / | / | / | ChIP-seq (anti-γH2AX) | |
GSM2891670-gh2ax_HeLa_INP_2_1 | HeLa | Homo sapiens | Doxycycline | WT | / | / | / | ChIP-seq (Input) | |
GSM2891671-gh2ax_HeLa_IP_2_1 | HeLa | Homo sapiens | Doxycycline | WT | / | / | / | ChIP-seq (anti-γH2AX) | |
GSM2891672-gh2ax_TOP1_IP_2_1 | HeLa | Homo sapiens | Doxycycline | shTOP1 | / | / | / | ChIP-seq (anti-γH2AX) | |
GSM2891682-gH2AX_U2OS_Ctrl_Inp | U2OS | Homo sapiens | Doxycycline | WT | / | / | / | ChIP-seq (Input) | |
GSM2891683-gH2AX_U2OS_Ctrl_IP | U2OS | Homo sapiens | Doxycycline | WT | / | / | / | ChIP-seq (anti-γH2AX) | |
GSM2891684-gH2AX_U2OS_AsiS1_Inp | U2OS | Homo sapiens | Doxycycline | shASF | / | / | AsiSI | ChIP-seq (Input) | |
GSM2891685-gH2AX_U2OS_AsiS1_IP | U2OS | Homo sapiens | Doxycycline | shASF | / | / | AsiSI | ChIP-seq (anti-γH2AX) | |
GSM4568568-B_HeLa_shTop1_S2_L002_R1_HWGLVBCXY_V2 | HeLa | Homo sapiens | NT | shTOP1 | / | / | / | i-BLESS | |
GSM4568567-B_HeLa_S1_L001_R1_HWGLVBCXY_V1 | HeLa | Homo sapiens | NT | WT | / | / | / | i-BLESS |
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