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DNA Damage Atlas |
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DNA Damage Atlas |
Basic Information
Dataset ID:
GSE77788
PMID:
28199309
Technique Type:
HTGTS
Publication:
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells
First Author:
Mara Compagno
Last Author:
Roberto Chiarle
Year:
2017
Journal:
Nature
Access Link:
Samples ( 73 )
| Sample Name | Cell Line/Tissue | Organism | Treatment | Genotype | In-situ Treatment | Cell Phase | Bait/Targeted Break | Technique | fastqc |
| GSM2059291-HTGTS_DMSO_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | DMSO | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059292-HTGTS_DMSO_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | DMSO | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059293-HTGTS_DMSO_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | DMSO | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059294-HTGTS_AS-604850_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | AS-604850 | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059295-HTGTS_AS-604850_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | AS-604850 | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059296-HTGTS_AS-604850_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | AS-604850 | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059297-HTGTS_Idelalisib_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | Idelalisib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059298-HTGTS_Idelalisib_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | Idelalisib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059299-HTGTS_Idelalisib_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | Idelalisib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059300-HTGTS_Duvelisib_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | Duvelisib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059301-HTGTS_Duvelisib_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | Duvelisib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059302-HTGTS_Duvelisib_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | Duvelisib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059303-HTGTS_Ibrutinib_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | Ibrutinib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059304-HTGTS_Ibrutinib_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | Ibrutinib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059305-HTGTS_Ibrutinib_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | Ibrutinib | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059306-HTGTS_KO-DMSO_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | DMSO | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059307-HTGTS_KO-DMSO_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | DMSO | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059308-HTGTS_KO-DMSO_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | DMSO | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059309-HTGTS_KO-Idelalisib_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | Idelalisib | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059310-HTGTS_KO-Idelalisib_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | Idelalisib | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059311-HTGTS_KO-Idelalisib_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | Idelalisib | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059312-HTGTS_KO-Duvelisib_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | Duvelisib | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059313-HTGTS_KO-Duvelisib_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | Duvelisib | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059314-HTGTS_KO-Duvelisib_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | Duvelisib | c-myc25xI-SceI AID-/- | / | / | / | HTGTS | |
| GSM2059315-HTGTS_PI3K-WT_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | / | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059316-HTGTS_PI3K-WT_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | / | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059317-HTGTS_PI3K-WT_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | / | c-myc25xI-SceI WT | / | / | / | HTGTS | |
| GSM2059318-HTGTS_PI3K-Mut_rep1 | anti-CD40 and Il4 activated B cell | Mus musculus | / | c-myc25xI-SceI / PI3K p110δ(E1021K) mutant | / | / | / | HTGTS | |
| GSM2059319-HTGTS_PI3K-Mut_rep2 | anti-CD40 and Il4 activated B cell | Mus musculus | / | c-myc25xI-SceI / PI3K p110δ(E1021K) mutant | / | / | / | HTGTS | |
| GSM2059320-HTGTS_PI3K-Mut_rep3 | anti-CD40 and Il4 activated B cell | Mus musculus | / | c-myc25xI-SceI / PI3K p110δ(E1021K) mutant | / | / | / | HTGTS | |
| GSM2059321-HTGTS_MEC1_DMSO_rep1 | MEC1 | Homo sapiens | DMSO | / | / | / | / | HTGTS | |
| GSM2059322-HTGTS_MEC1_DMSO_rep2 | MEC1 | Homo sapiens | DMSO | / | / | / | / | HTGTS | |
| GSM2059323-HTGTS_MEC1_Idelalisib_rep1 | MEC1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059324-HTGTS_MEC1_Idelalisib_rep2 | MEC1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059325-HTGTS_MEC1_Idelalisib_rep3 | MEC1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059326-HTGTS_MEC1_Idelalisib_rep4 | MEC1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059327-HTGTS_MEC1_Duvelisib_rep1 | MEC1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059328-HTGTS_MEC1_Duvelisib_rep2 | MEC1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059329-HTGTS_MEC1_Duvelisib_rep3 | MEC1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059330-HTGTS_MEC1_Duvelisib_rep4 | MEC1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059331-HTGTS_MEC1_Ibrutinib_rep1 | MEC1 | Homo sapiens | Ibrutinib | / | / | / | / | HTGTS | |
| GSM2059332-HTGTS_MEC1_Ibrutinib_rep2 | MEC1 | Homo sapiens | Ibrutinib | / | / | / | / | HTGTS | |
| GSM2059333-HTGTS_MEC1_Ibrutinib_rep3 | MEC1 | Homo sapiens | Ibrutinib | / | / | / | / | HTGTS | |
| GSM2059334-HTGTS_MEC1_Ibrutinib_rep4 | MEC1 | Homo sapiens | Ibrutinib | / | / | / | / | HTGTS | |
| GSM2059335-HTGTS_JeKo-1_DMSO_rep1 | JeKo-1 | Homo sapiens | DMSO | / | / | / | / | HTGTS | |
| GSM2059336-HTGTS_JeKo-1_DMSO_rep2 | JeKo-1 | Homo sapiens | DMSO | / | / | / | / | HTGTS | |
| GSM2059337-HTGTS_JeKo-1_DMSO_rep3 | JeKo-1 | Homo sapiens | DMSO | / | / | / | / | HTGTS | |
| GSM2059338-HTGTS_JeKo-1_DMSO_rep4 | JeKo-1 | Homo sapiens | DMSO | / | / | / | / | HTGTS | |
| GSM2059339-HTGTS_JeKo-1_Idelalisib_rep1 | JeKo-1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059340-HTGTS_JeKo-1_Idelalisib_rep2 | JeKo-1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059341-HTGTS_JeKo-1_Idelalisib_rep3 | JeKo-1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059342-HTGTS_JeKo-1_Idelalisib_rep4 | JeKo-1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059343-HTGTS_JeKo-1_Idelalisib_rep5 | JeKo-1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059344-HTGTS_JeKo-1_Idelalisib_rep6 | JeKo-1 | Homo sapiens | Idelalisib | / | / | / | / | HTGTS | |
| GSM2059345-HTGTS_JeKo-1_Duvelisib_rep1 | JeKo-1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059346-HTGTS_JeKo-1_Duvelisib_rep2 | JeKo-1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059347-HTGTS_JeKo-1_Duvelisib_rep3 | JeKo-1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059348-HTGTS_JeKo-1_Duvelisib_rep4 | JeKo-1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059349-HTGTS_JeKo-1_Duvelisib_rep5 | JeKo-1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2059350-HTGTS_JeKo-1_Ibrutinib_rep1 | JeKo-1 | Homo sapiens | Ibrutinib | / | / | / | / | HTGTS | |
| GSM2059351-HTGTS_JeKo-1_Ibrutinib_rep2 | JeKo-1 | Homo sapiens | Ibrutinib | / | / | / | / | HTGTS | |
| GSM2059352-HTGTS_JeKo-1_Ibrutinib_rep3 | JeKo-1 | Homo sapiens | Ibrutinib | / | / | / | / | HTGTS | |
| GSM2430305-HTGTS_MEC1_Duvelisib_rep5 | MEC1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2430306-HTGTS_MEC1_Duvelisib_rep6 | MEC1 | Homo sapiens | Duvelisib | / | / | / | / | HTGTS | |
| GSM2430307-HTGTS_MEC1_KO-DMSO_rep1 | MEC1 | Homo sapiens | DMSO | AID-/- | / | / | / | HTGTS | |
| GSM2430308-HTGTS_MEC1_KO-DMSO_rep2 | MEC1 | Homo sapiens | DMSO | AID-/- | / | / | / | HTGTS | |
| GSM2430309-HTGTS_MEC1_KO-DMSO_rep3 | MEC1 | Homo sapiens | DMSO | AID-/- | / | / | / | HTGTS | |
| GSM2430310-HTGTS_MEC1_KO-Idelalisib_rep1 | MEC1 | Homo sapiens | Idelalisib | AID-/- | / | / | / | HTGTS | |
| GSM2430311-HTGTS_MEC1_KO-Idelalisib_rep2 | MEC1 | Homo sapiens | Idelalisib | AID-/- | / | / | / | HTGTS | |
| GSM2430312-HTGTS_MEC1_KO-Idelalisib_rep3 | MEC1 | Homo sapiens | Idelalisib | AID-/- | / | / | / | HTGTS | |
| GSM2430313-HTGTS_MEC1_KO-Duvelisib_rep1 | MEC1 | Homo sapiens | Duvelisib | AID-/- | / | / | / | HTGTS | |
| GSM2430314-HTGTS_MEC1_KO-Duvelisib_rep2 | MEC1 | Homo sapiens | Duvelisib | AID-/- | / | / | / | HTGTS | |
| GSM2430315-HTGTS_MEC1_KO-Duvelisib_rep3 | MEC1 | Homo sapiens | Duvelisib | AID-/- | / | / | / | HTGTS |
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