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DNA Damage Atlas |
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DNA Damage Atlas |
Basic Information
Dataset ID:
GSE130216
PMID:
31511698
Technique Type:
HTGTS V(D)J-seq
Publication:
The fundamental role of chromatin loop extrusion in physiological V(D)J recombination
First Author:
Yu Zhang
Last Author:
Frederick W Alt
Year:
2019
Journal:
Nature
Access Link:
Samples ( 76 )
| Sample Name | Cell Line/Tissue | Organism | Treatment | Genotype | In-situ Treatment | Cell Phase | Bait/Targeted Break | Technique | fastqc |
| GSM3733975-DHJH_JH1bait_set1_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733976-DHJH_JH1bait_set1_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733977-DHJH_JH1bait_set1_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733978-DHJH_JH1bait_set2_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733979-DHJH_JH1bait_set2_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733980-DHJH_JH1bait_set2_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733981-DHJH_DFL16_1RSSUP_inv_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1-RSS-UP inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733982-DHJH_DFL16_1RSSUP_inv_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1-RSS-UP inversion, Emu-Bcl2 | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733983-DHJH_DFL16_1RSSUP_inv_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1-RSS-UP inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733984-DHJH_DFL16_1RSSDN_inv_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1-RSS-DN inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733985-DHJH_DFL16_1RSSDN_inv_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1-RSS-DN inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733986-DHJH_DFL16_1RSSDN_inv_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1-RSS-DN inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733987-DHJH_DFL16_1_inv_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733988-DHJH_DFL16_1_inv_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733989-DHJH_DFL16_1_inv_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733990-DHJH_DFL16_1_inv_JH1bait_rep4 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733991-DHJH_DFL16_1_inv_JH1bait_rep5 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, DFL16.1 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733992-JH1 _JH1bait_set1_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733993-JH1 _JH1bait_set1_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733994-JH1 _JH1bait_set1_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733995-JH1 _JH1bait_set2_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733996-JH1 _JH1bait_set2_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733997-JH1 _JH1bait_set2_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733998-JH1_intervening_DH_inv_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, intervening DH inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3733999-JH1_intervening_DH_inv_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, intervening DH inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734000-JH1_intervening_DH_inv_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, intervening DH inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734001-JH1_DQ52_inv_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734002-JH1_DQ52_inv_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734003-JH1_DQ52_inv_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734004-JH1_DQ52replaceDFL16_1_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52-del, DFL16.1 replaced by DQ52, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734005-JH1_DQ52replaceDFL16_1_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52-del, DFL16.1 replaced by DQ52, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734006-JH1_DQ52replaceDFL16_1_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52-del, DFL16.1 replaced by DQ52, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734007-JH1_DQ52inv_replaceDFL16_1_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52-del, DFL16.1 replaced by DQ52-inv, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734008-JH1_DQ52inv_replaceDFL16_1_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52-del, DFL16.1 replaced by DQ52-inv, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734009-JH1_DQ52inv_replaceDFL16_1_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DQ52-del, DFL16.1 replaced by DQ52-inv, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734010-JH1_DFL16_1replaceDQ52_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DFL16.1-del, DQ52 replaced by DFL16.1, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734011-JH1_DFL16_1replaceDQ52_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DFL16.1-del, DQ52 replaced by DFL16.1, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734012-JH1_DFL16_1replaceDQ52_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DFL16.1-del, DQ52 replaced by DFL16.1, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734013-JH1_DFL16_1inv_replaceDQ52_JH1bait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DFL16.1-del, DQ52 replaced by DFL16.1 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734014-JH1_DFL16_1inv_replaceDQ52_JH1bait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DFL16.1-del, DQ52 replaced by DFL16.1 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734015-JH1_DFL16_1inv_replaceDQ52_JH1bait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH1+/-, DFL16.1-del, DQ52 replaced by DFL16.1 inversion, Emu-Bcl2, RAG2 deficient | / | / | JH1bait | HTGTS V(D)J-seq | |
| GSM3734016-JHdel_DQ52RSSUPbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-UP bait | HTGTS V(D)J-seq | |
| GSM3734017-JHdel_DQ52RSSUPbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-UP bait | HTGTS V(D)J-seq | |
| GSM3734018-JHdel_DQ52RSSUPbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-UP bait | HTGTS V(D)J-seq | |
| GSM3734019-JHdel_DQ52RSSDNbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734020-JHdel_DQ52RSSDNbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734021-JHdel_DQ52RSSDNbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734022-dCas9Control_DQ52RSSDNbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734023-dCas9Control_DQ52RSSDNbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734024-dCas9Control_DQ52RSSDNbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734025-dCas9Control_DQ52RSSDNbait_rep4 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734026-dCas9Control_DQ52RSSDNbait_rep5 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734027-dCas9Block_DQ52RSSDNbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del,dCas9 expressing, Sg1-sgRNA expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734028-dCas9Block_DQ52RSSDNbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del,dCas9 expressing, Sg1-sgRNA expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734029-dCas9Block_DQ52RSSDNbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del,dCas9 expressing, Sg1-sgRNA expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734030-dCas9Block_DQ52RSSDNbait_rep4 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del,dCas9 expressing, Sg1-sgRNA expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734031-dCas9Block_DQ52RSSDNbait_rep5 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del,dCas9 expressing, Sg1-sgRNA expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734032-Ig2bwt_DQ52RSSDNbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734033-Ig2bwt_DQ52RSSDNbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734034-Ig2bwt_DQ52RSSDNbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-delta-dCas9, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734035-Ig2bdel_DQ52RSSDNbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Ig2b-del/del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734036-Ig2bdel_DQ52RSSDNbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Ig2b-del/del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734037-Ig2bdel_DQ52RSSDNbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | JH-del, dCas9 expressing, Ig2b-del/del, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3734038-DFL16_1JH4_DJHRSSbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734039-DFL16_1JH4_DJHRSSbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734040-DFL16_1JH4_DJHRSSbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734041-DFL16_1JH4inv_DJHRSSbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4-inv, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734042-DFL16_1JH4inv_DJHRSSbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4-inv, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734043-DFL16_1JH4inv_DJHRSSbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4-inv, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734044-DFL16_1JH4inv_DJHRSSbait_rep4 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4-inv, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734045-DFL16_1JH4inv_3CBEsdel_DJHRSSbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4-inv, 3'CBEs-del/del, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734046-DFL16_1JH4inv_3CBEsdel_DJHRSSbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4-inv, 3'CBEs-del/del, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3734047-DFL16_1JH4inv_3CBEsdel_DJHRSSbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DFL16.1JH4-inv, 3'CBEs-del/del, Emu-Bcl2 | / | / | DJH-RSS bait | HTGTS V(D)J-seq | |
| GSM3963082-DHJH_DQ52RSSDNbait_rep1 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3963083-DHJH_DQ52RSSDNbait_rep2 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq | |
| GSM3963084-DHJH_DQ52RSSDNbait_rep3 | v-Abl transformed pro-B cell | Mus musculus | STI-571 | DH-JH+/-, Emu-Bcl2, RAG2 deficient | / | / | DQ52-RSS-DN bait | HTGTS V(D)J-seq |
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