DNA Damage Atlas



Basic Information

Dataset ID:

  GSE149706


PMID:

  32999459


Technique Type:

  END-seq


Publication:

  Repeat expansions confer WRN dependence in microsatellite-unstable cancers


First Author:

  Niek van Wietmarschen


Last Author:

  André Nussenzweig


Year:

  2021


Journal:

  Nature


Access Link:   

Samples ( 34 )

  Sample Name    Cell Line/Tissue    Organism    Treatment    Genotype    In-situ Treatment    Cell Phase    Bait/Targeted Break    Technique    fastqc  
GSM4509216-ENDseq-KM12-DOX-rep1KM12Homo sapiensDoxycyclineDox inducible shWRNExo VII + Exo T//END-seq
GSM4509217-ENDseq-KM12-NT-rep1KM12Homo sapiensNTDox inducible shWRNExo VII + Exo T//END-seq
GSM4509218-ENDseq-KM12-DOX-rep2KM12Homo sapiensDoxycyclineDox inducible shWRNExo VII + Exo T//END-seq
GSM4509219-ENDseq-KM12-NT-rep2KM12Homo sapiensNTDox inducible shWRNExo VII + Exo T//END-seq
GSM4509220-ENDseq-HCT116-DOX-rep1HCT116Homo sapiensDoxycyclineDox inducible shWRNExo VII + Exo T//END-seq
GSM4509221-ENDseq-HCT116-NT-rep1HCT116Homo sapiensNTDox inducible shWRNExo VII + Exo T//END-seq
GSM4509222-ENDseq-HCT116-DOX-rep2HCT116Homo sapiensDoxycyclineDox inducible shWRNExo VII + Exo T//END-seq
GSM4509223-ENDseq-HCT116-NT-rep2HCT116Homo sapiensNTDox inducible shWRNExo VII + Exo T//END-seq
GSM4509224-ENDseq-KM12-siWRNKM12Homo sapiensWRN siRNAsDox inducible shWRNExo VII + Exo T//END-seq
GSM4509225-ENDseq-KM12-siCTRLKM12Homo sapiensnon-targeting siRNAsDox inducible shWRNExo VII + Exo T//END-seq
GSM4509226-ENDseq-HCT116-siWRNHCT116Homo sapiensWRN siRNAsWTExo VII + Exo T//END-seq
GSM4509227-ENDseq-HCT116-siCTRLHCT116Homo sapiensnon-targeting siRNAsWTExo VII + Exo T//END-seq
GSM4509228-ENDseq-SW837-DOXSW837Homo sapiensDoxycyclineDox inducible shWRNExo VII + Exo T//END-seq
GSM4509229-ENDseq-KM12-DOX-siCTRLKM12Homo sapiensDoxycycline + non-targeting siRNAsDox inducible shWRNExo VII + Exo T//END-seq
GSM4509230-ENDseq-KM12-DOX-siMUS81KM12Homo sapiensDoxycycline + MUS81 siRNAsDox inducible shWRNExo VII + Exo T//END-seq
GSM4509231-ENDseq-KM12-DOX-siSLX4KM12Homo sapiensDoxycycline + SLX4 siRNAsDox inducible shWRNExo VII + Exo T//END-seq
GSM4509232-ENDseq-KM12-MUS81-EME1-rep1KM12Homo sapiens/Dox inducible shWRNExo VII + Exo T + MUS81-EME1//END-seq
GSM4509233-ENDseq-KM12-NT-for-MUS81-EME1-rep1KM12Homo sapiens/Dox inducible shWRNExo VII + Exo T//END-seq
GSM4509234-ENDseq-KM12-MUS81-EME1-rep2KM12Homo sapiens/Dox inducible shWRNExo VII + Exo T + MUS81-EME1//END-seq
GSM4509235-ENDseq-KM12-NT-for-MUS81-EME1-rep2KM12Homo sapiens/Dox inducible shWRNExo VII + Exo T//END-seq
GSM4509236-ENDseq-KM12-WRNKM12Homo sapiens/Dox inducible shWRNExo VII + Exo T//END-seq
GSM4509237-ENDseq-KM12-WRN-ATP-ProK-MUS81-EME1KM12Homo sapiensATP followed by proteinse KDox inducible shWRNExo VII + Exo T + MUS81-EME1//END-seq
GSM4509238-ENDseq-HCT116-MUS81-EME1HCT116Homo sapiens/Dox inducible shWRNExo VII + Exo T + MUS81-EME1//END-seq
GSM4509239-ENDseq-HCT116-NT-for-MUS81-EME1HCT116Homo sapiens/Dox inducible shWRNExo VII + Exo T//END-seq
GSM4509240-ENDseq-SW837-MUS81-EME1SW837Homo sapiens/Dox inducible shWRNExo VII + Exo T + MUS81-EME1//END-seq
GSM4509241-ENDseq-RPE1-MUS81-EME1RPE1Homo sapiens/Dox inducible shWRNExo VII + Exo T + MUS81-EME1//END-seq
GSM4663366-ENDSeq-KM12-APH-ATRiKM12Homo sapiensAphidicolin + ATR inhibitorDox inducible shWRNExo VII + Exo T//END-seq
GSM4663367-ENDseq-KM12-NT-for-APH-ATRiKM12Homo sapiensNTDox inducible shWRNExo VII + Exo T//END-seq
GSM4663368-ENDseq-HCT116-APH-ATRiHCT116Homo sapiensAphidicolin + ATR inhibitorWTExo VII + Exo T//END-seq
GSM4663369-ENDseq-HCT116-NT-for-APH-ATRiHCT116Homo sapiensNTWTExo VII + Exo T//END-seq
GSM4663370-ENDseq-RPE1-APH-ATRiRPE1Homo sapiensAphidicolin + ATR inhibitorWTExo VII + Exo T//END-seq
GSM4663371-ENDseq-RPE1-NT-for-APH-ATRiRPE1Homo sapiensNTWTExo VII + Exo T//END-seq
GSM4663372-ENDseq-eHAP-APH-ATRieHAPHomo sapiensAphidicolin + ATR inhibitorDox inducible shWRNExo VII + Exo T//END-seq
GSM4663373-ENDseq-eHAP-NT-for-APH-ATRieHAPHomo sapiensNTDox inducible shWRNExo VII + Exo T//END-seq


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