Dataset Detail

Basic Information

Dataset ID:

GSE140372

PMID:

32057297

Technique Type:

END-seq

Publication:

Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity

First Author:

Nicholas Sciascia

Last Author:

André Nussenzweig

Year:

2020

Journal:

eLife

Access Link:

Samples ( 35 )

Sample Name	Cell Line/Tissue	Organism	Treatment	Genotype	In-situ Treatment	Cell Phase	Bait/Targeted Break	Technique	fastqc
GSM4160241-NT	Primary B cell	Mus musculus	NT	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160242-ETO	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160243-ETO_WO	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160244-ETO_WO_2h	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160245-BTZ	Primary B cell	Mus musculus	Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160246-ETO--BTZ	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160247-ETO--BTZ_WO	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160248-ETO--BTZ_WO_2h	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160249-ETO_Exo7--ExoT	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160250-ETO_ExoT	Primary B cell	Mus musculus	Etoposide	WT	Exo T	G1	/	END-seq
GSM4160251-ETO_WO_Exo7--ExoT	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160252-ETO_WO_ExoT	Primary B cell	Mus musculus	Etoposide	WT	Exo T	G1	/	END-seq
GSM4160253-ETO--BTZ_Exo7--ExoT	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160254-ETO--BTZ_ExoT	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo T	G1	/	END-seq
GSM4160255-ETO--BTZ_WO_Exo7--ExoT	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160256-ETO--BTZ_WO_ExoT	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo T	G1	/	END-seq
GSM4160257-pre-BTZ--ETO	Primary B cell	Mus musculus	pre-Bortezomib + Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160258-pre-BTZ--ETO_WO_2h	Primary B cell	Mus musculus	pre-Bortezomib + Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160259-co-BTZ--ETO	Primary B cell	Mus musculus	Etoposide co-treatment with Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160260-co-BTZ--ETO_WO_2h	Primary B cell	Mus musculus	Etoposide co-treatment with Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160261-post-BTZ--ETO_WO_2h	Primary B cell	Mus musculus	Etoposide post-treatment with Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160262-no_BTZ--ETO	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160263-no_BTZ--ETO_WO_2h	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160264-WT_ETO_Exo7--ExoT	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4160265-RNF4_ETO_Exo7--ExoT	Primary B cell	Mus musculus	Etoposide	RNF4^-/-	Exo VII + Exo T	G1	/	END-seq
GSM4160266-WT_ETO_ExoT_only	Primary B cell	Mus musculus	Etoposide	WT	Exo T	G1	/	END-seq
GSM4160267-RNF4_ETO_ExoT_only	Primary B cell	Mus musculus	Etoposide	RNF4^-/-	Exo T	G1	/	END-seq
GSM4207022-NT_rep2	Primary B cell	Mus musculus	NT	WT	Exo VII + Exo T	G1	/	END-seq
GSM4207023-ETO_rep2	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4207024-ETO_WO_rep2	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4207025-ETO_WO_2h_rep2	Primary B cell	Mus musculus	Etoposide	WT	Exo VII + Exo T	G1	/	END-seq
GSM4207026-BTZ_rep2	Primary B cell	Mus musculus	Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4207027-ETO--BTZ_rep2	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4207028-ETO--BTZ_WO_rep2	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq
GSM4207029-ETO--BTZ_WO_2h_rep2	Primary B cell	Mus musculus	Etoposide + Bortezomib	WT	Exo VII + Exo T	G1	/	END-seq