DNA Damage Atlas



Basic Information

Dataset ID:

  GSE129524


PMID:

  31202577


Technique Type:

  END-seq


Publication:

  Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity


First Author:

  Andres Canela


Last Author:

  André Nussenzweig


Year:

  2019


Journal:

  Molecular Cell


Access Link:   

Samples ( 48 )

  Sample Name    Cell Line/Tissue    Organism    Treatment    Genotype    In-situ Treatment    Cell Phase    Bait/Targeted Break    Technique    fastqc  
GSM3714864-END_seq_PB_LIG4_2_5h_TRANSLOCATIONAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714865-END_seq_PB_LIG4_AsiSI_TRANSLOCATIONAbel pre-B cellMus musculus/Lig4-/-Exo VII + Exo TG1AsiSIEND-seq
GSM3714866-END_seq_PB_LIG4_2_5h_DRB_TRXAbel pre-B cellMus musculusDRB + EtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714867-END_seq_ExoT_PB_LIG4_2_5h_DRB_TRXAbel pre-B cellMus musculusDRB + EtoposideLig4-/-Exo TG1/END-seq
GSM3714868-END_seq_PB_LIG4_AsiSI_DRB_TRXAbel pre-B cellMus musculusDRBLig4-/-Exo VII + Exo TG1AsiSIEND-seq
GSM3714869-END_seq_PB_LIG4_2_5h_IFNB_TRXAbel pre-B cellMus musculusIFNβ + EtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714870-END_seq_ExoT_PB_LIG4_2_5h_IFNB_TRXAbel pre-B cellMus musculusIFNβ + EtoposideLig4-/-Exo TG1/END-seq
GSM3714871-END_seq_PB_LIG4_0_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714872-END_seq_PB_LIG4_1h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714873-END_seq_PB_LIG4_2_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714874-END_seq_PB_LIG4_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714875-END_seq_PB_LIG4_7_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714876-END_seq_PB_LIG4_12_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714877-END_seq_ExoT_PB_LIG4_0_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714878-END_seq_ExoT_PB_LIG4_1h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714879-END_seq_ExoT_PB_LIG4_2_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714880-END_seq_ExoT_PB_LIG4_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714881-END_seq_ExoT_PB_LIG4_7_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714882-END_seq_ExoT_PB_LIG4_12_5h_TIME_COURSEAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714883-END_seq_PB_LIG4_NT_controlAbel pre-B cellMus musculusNTLig4-/-Exo VII + Exo TG1/END-seq
GSM3714884-END_seq_ExoT_PB_LIG4_NT_controlAbel pre-B cellMus musculusNTLig4-/-Exo TG1/END-seq
GSM3714885-END_seq_PB_LIG4_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714886-END_seq_ExoT_PB_LIG4_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714887-END_seq_PB_LIG4_WASH_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714888-END_seq_ExoT_PB_LIG4_WASH_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714889-END_seq_PB_LIG4_TDP2_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/- TDP2-/-Exo VII + Exo TG1/END-seq
GSM3714890-END_seq_ExoT_PB_LIG4_TDP2_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/- TDP2-/-Exo TG1/END-seq
GSM3714891-END_seq_PB_LIG4_TDP2_WASH_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/- TDP2-/-Exo VII + Exo TG1/END-seq
GSM3714892-END_seq_ExoT_PB_LIG4_TDP2_WASH_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/- TDP2-/-Exo TG1/END-seq
GSM3714893-END_seq_PB_LIG4_EPOX_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEpoxomicin + EtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714894-END_seq_ExoT_PB_LIG4_EPOX_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEpoxomicin + EtoposideLig4-/-Exo TG1/END-seq
GSM3714895-END_seq_PB_LIG4_EPOX_WASH_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEpoxomicin + EtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714896-END_seq_ExoT_PB_LIG4_EPOX_WASH_2_5h_REVERSIBILITYAbel pre-B cellMus musculusEpoxomicin + EtoposideLig4-/-Exo TG1/END-seq
GSM3714897-END_seq_PB_LIG4_WASH_0_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/-Exo VII + Exo TG1/END-seq
GSM3714898-END_seq_ExoT_PB_LIG4_WASH_0_5h_REVERSIBILITYAbel pre-B cellMus musculusEtoposideLig4-/-Exo TG1/END-seq
GSM3714899-END_seq_MEF_Smc3_PP_0_5hMEFMus musculusEtoposideWTExo VII + Exo T//END-seq
GSM3714900-END_seq_MEF_Smc3_FF_0_5hMEFMus musculusEtoposideSmc3f/f+CREExo VII + Exo T//END-seq
GSM3714901-END_seq_MEF_Wapl_FF_0_5h_controlMEFMus musculusEtoposideWaplf/fExo VII + Exo T//END-seq
GSM3714902-END_seq_MEF_Wapl_FF_CRE_0_5hMEFMus musculusEtoposideWaplf/f+CREExo VII + Exo T//END-seq
GSM3714903-END_seq_HCT116_0_5hHCT116Homo sapiensEtoposideWTExo VII + Exo TG1/END-seq
GSM3714904-END_seq_HCT116__RAD21_AID_0_5hHCT116Homo sapiensEtoposideRAD21 AIDExo VII + Exo TG1/END-seq
GSM3714905-END_seq_HCT116_NT_controlHCT116Homo sapiensNTWTExo VII + Exo TG1/END-seq
GSM3714906-END_seq_aB_TOP2Bko_0_5h_rep1Reconsituted B cellMus musculusEtoposideTOP2B-/-Exo VII + Exo T//END-seq
GSM3714907-END_seq_aB_TOP2Bko_0_5h_rep2Reconsituted B cellMus musculusEtoposideTOP2B-/-Exo VII + Exo T//END-seq
GSM3714908-END_seq_aB_WT_0_5h_rep1Reconsituted B cellMus musculusEtoposideWTExo VII + Exo T//END-seq
GSM3714909-END_seq_aB_WT_0_5h_rep2Reconsituted B cellMus musculusEtoposideWTExo VII + Exo T//END-seq
GSM3714910-END_seq_MEF_NT_re-usedMEFMus musculusNTWTExo VII + Exo T//END-seq
GSM3714911-END_seq_aB12h_NT_re-usedActivated primary B cellMus musculusNTWTExo VII + Exo T//END-seq


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