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DNA Damage Atlas |
Basic Information
Dataset ID:
 GSE129524
PMID:
 31202577
Technique Type:
 END-seq
Publication:
 Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity
First Author:
 Andres Canela
Last Author:
 André Nussenzweig
Year:
 2019
Journal:
 Molecular Cell
Access Link:  
Samples ( 48 )
Sample Name | Cell Line/Tissue | Organism | Treatment | Genotype | In-situ Treatment | Cell Phase | Bait/Targeted Break | Technique | fastqc |
GSM3714864-END_seq_PB_LIG4_2_5h_TRANSLOCATION | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714865-END_seq_PB_LIG4_AsiSI_TRANSLOCATION | Abel pre-B cell | Mus musculus | / | Lig4-/- | Exo VII + Exo T | G1 | AsiSI | END-seq | |
GSM3714866-END_seq_PB_LIG4_2_5h_DRB_TRX | Abel pre-B cell | Mus musculus | DRB + Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714867-END_seq_ExoT_PB_LIG4_2_5h_DRB_TRX | Abel pre-B cell | Mus musculus | DRB + Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714868-END_seq_PB_LIG4_AsiSI_DRB_TRX | Abel pre-B cell | Mus musculus | DRB | Lig4-/- | Exo VII + Exo T | G1 | AsiSI | END-seq | |
GSM3714869-END_seq_PB_LIG4_2_5h_IFNB_TRX | Abel pre-B cell | Mus musculus | IFNβ + Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714870-END_seq_ExoT_PB_LIG4_2_5h_IFNB_TRX | Abel pre-B cell | Mus musculus | IFNβ + Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714871-END_seq_PB_LIG4_0_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714872-END_seq_PB_LIG4_1h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714873-END_seq_PB_LIG4_2_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714874-END_seq_PB_LIG4_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714875-END_seq_PB_LIG4_7_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714876-END_seq_PB_LIG4_12_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714877-END_seq_ExoT_PB_LIG4_0_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714878-END_seq_ExoT_PB_LIG4_1h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714879-END_seq_ExoT_PB_LIG4_2_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714880-END_seq_ExoT_PB_LIG4_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714881-END_seq_ExoT_PB_LIG4_7_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714882-END_seq_ExoT_PB_LIG4_12_5h_TIME_COURSE | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714883-END_seq_PB_LIG4_NT_control | Abel pre-B cell | Mus musculus | NT | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714884-END_seq_ExoT_PB_LIG4_NT_control | Abel pre-B cell | Mus musculus | NT | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714885-END_seq_PB_LIG4_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714886-END_seq_ExoT_PB_LIG4_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714887-END_seq_PB_LIG4_WASH_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714888-END_seq_ExoT_PB_LIG4_WASH_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714889-END_seq_PB_LIG4_TDP2_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- TDP2-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714890-END_seq_ExoT_PB_LIG4_TDP2_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- TDP2-/- | Exo T | G1 | / | END-seq | |
GSM3714891-END_seq_PB_LIG4_TDP2_WASH_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- TDP2-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714892-END_seq_ExoT_PB_LIG4_TDP2_WASH_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- TDP2-/- | Exo T | G1 | / | END-seq | |
GSM3714893-END_seq_PB_LIG4_EPOX_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Epoxomicin + Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714894-END_seq_ExoT_PB_LIG4_EPOX_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Epoxomicin + Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714895-END_seq_PB_LIG4_EPOX_WASH_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Epoxomicin + Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714896-END_seq_ExoT_PB_LIG4_EPOX_WASH_2_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Epoxomicin + Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714897-END_seq_PB_LIG4_WASH_0_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714898-END_seq_ExoT_PB_LIG4_WASH_0_5h_REVERSIBILITY | Abel pre-B cell | Mus musculus | Etoposide | Lig4-/- | Exo T | G1 | / | END-seq | |
GSM3714899-END_seq_MEF_Smc3_PP_0_5h | MEF | Mus musculus | Etoposide | WT | Exo VII + Exo T | / | / | END-seq | |
GSM3714900-END_seq_MEF_Smc3_FF_0_5h | MEF | Mus musculus | Etoposide | Smc3f/f+CRE | Exo VII + Exo T | / | / | END-seq | |
GSM3714901-END_seq_MEF_Wapl_FF_0_5h_control | MEF | Mus musculus | Etoposide | Waplf/f | Exo VII + Exo T | / | / | END-seq | |
GSM3714902-END_seq_MEF_Wapl_FF_CRE_0_5h | MEF | Mus musculus | Etoposide | Waplf/f+CRE | Exo VII + Exo T | / | / | END-seq | |
GSM3714903-END_seq_HCT116_0_5h | HCT116 | Homo sapiens | Etoposide | WT | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714904-END_seq_HCT116__RAD21_AID_0_5h | HCT116 | Homo sapiens | Etoposide | RAD21 AID | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714905-END_seq_HCT116_NT_control | HCT116 | Homo sapiens | NT | WT | Exo VII + Exo T | G1 | / | END-seq | |
GSM3714906-END_seq_aB_TOP2Bko_0_5h_rep1 | Reconsituted B cell | Mus musculus | Etoposide | TOP2B-/- | Exo VII + Exo T | / | / | END-seq | |
GSM3714907-END_seq_aB_TOP2Bko_0_5h_rep2 | Reconsituted B cell | Mus musculus | Etoposide | TOP2B-/- | Exo VII + Exo T | / | / | END-seq | |
GSM3714908-END_seq_aB_WT_0_5h_rep1 | Reconsituted B cell | Mus musculus | Etoposide | WT | Exo VII + Exo T | / | / | END-seq | |
GSM3714909-END_seq_aB_WT_0_5h_rep2 | Reconsituted B cell | Mus musculus | Etoposide | WT | Exo VII + Exo T | / | / | END-seq | |
GSM3714910-END_seq_MEF_NT_re-used | MEF | Mus musculus | NT | WT | Exo VII + Exo T | / | / | END-seq | |
GSM3714911-END_seq_aB12h_NT_re-used | Activated primary B cell | Mus musculus | NT | WT | Exo VII + Exo T | / | / | END-seq |
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